ErbB4 / DyLight 594 / HFR1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-2662DL594 (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen ErbB4
Clone HFR1
Host Mouse
Isotype IgG2b
Conjugate DyLight 594
Target Species Human, Mouse
Applications WB, FC, IHC, ICC/IF
Description Mouse ErbB4/Her4 antibody reacts with Human, Mouse [DyLight 594]
About ErbB4 and DyLight 594
ErbB4 This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra