CD324 / PE-ATTO 594 / 4A2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54587PEATT594 (View supplier product page)
Size 0.1 ml
Price $629.00
Antigen CD324
Clone 4A2
Host Mouse
Isotype IgG1 κ
Conjugate PE-ATTO 594
Target Species Human, Mouse, Rat
Applications FC
Description Mouse E-Cadherin antibody [PE-Atto594] detects Human, Mouse, Rat
About CD324 and PE-ATTO 594
CD324 This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
PE-ATTO 594 PE-ATTO 594 from ATTO-TEC has an excitation peak at 565 nm and an emission peak at 627 nm. It is an alternative to PE-Dazzle 594, PE-Alexa 610, PE-eFluor™ 610 and PE-CF®594.
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PE-ATTO 594 Excitation and Emission Spectra