DUX4 / Alexa Fluor 350 / P4H2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-49552AF350 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen DUX4
Clone P4H2
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 350
Target Species Human
Applications WB, IHC, ICC/IF, IHC-P, IHC-Fr
Description This antibody is specific for DUX4 and does not recognize DUX4c.
About DUX4 and Alexa Fluor 350
DUX4 This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra