C-Myc / Alexa Fluor 350 / 90000000000

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB600-302AF350 (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen C-Myc
Clone 90000000000
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 350
Target Species Drosophila, Human, Mouse
Applications WB, FC, ELISA, IHC, ICC/IF, IHC-P, IHC-Fr, ICFC
Description Specific for the c-myc protein in random coil configuration, not as a helix. 9E10 does not react with V-myc.
About C-Myc and Alexa Fluor 350
C-Myc This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra