SREBP1 / Alexa Fluor 700 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-60545AF700 (View supplier product page)
Size 100 μl
Price $399.00
Antigen SREBP1
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 700
Target Species Hamster, Human, Mouse, Rat
Applications WB
Description Rabbit SREBP1 antibody [Alexa Fluor 700] reacts with Human, Mouse, Rat, Hamster
About SREBP1 and Alexa Fluor 700
SREBP1 This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra