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	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-33144PEATT594 (View supplier product page)
	Size	0.1 ml
	Price	$569.00
	Antigen	CD45RA
	Clone	158-4D3
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	PE-ATTO 594
	Target Species	Human, Primate
	Applications	FC
	Description	Recognizes a protein of 205kDa-220kDa, identified as CD45RA [Workshop V; Code CD45.38]. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

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$569.00
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CD45RA / PE-ATTO 594 / 158-4D3