CD28 / DyLight 594 / 204.12

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54769DL594 (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen CD28
Clone 204.12
Host Mouse
Isotype IgG2a κ
Conjugate DyLight 594
Target Species Human, Mouse, Porcine, Primate, Sheep
Applications FC, IF
Description Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
About CD28 and DyLight 594
CD28 The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra