CD11b / Alexa Fluor 532 / M1/70.15

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB600-1327AF532 (View supplier product page)
Size 0.1 ml
Price $459.00
Antigen CD11b
Clone M1/70.15
Host Rat
Isotype IgG2b λ
Conjugate Alexa Fluor 532
Target Species Human, Mouse, Rabbit
Applications FC, IHC, ICC/IF, IHC-P, IHC-Fr
Description Rat CD11b antibody [Alexa Fluor 532] detects Human, Mouse, Rabbit
About CD11b and Alexa Fluor 532
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra