MCP-1 / Alexa Fluor 750 / 2D8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-22115AF750 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen MCP-1
Clone 2D8
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 750
Target Species Human, Mouse, Primate
Applications WB, FC, ELISA, IHC, ICC/IF, IHC-P
Description Mouse CCL2/MCP1 antibody [Alexa Fluor 750] reacts with Human, Mouse, Primate
About MCP-1 and Alexa Fluor 750
MCP-1 This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 750 Excitation and Emission Spectra