ATG5 / DyLight 350 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-53818UV (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen ATG5
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 350
Target Species Bovine, Fish, Guinea Pig, Human, Mouse, Porcine, Primate, Rat, Xenopus, Zebrafish
Applications WB, FC, IHC, ICC/IF, IHC-P, Knockout Validated
Description This is selective for the full-length and calpain cleaved isoform proteins. The short isoform is missing amino acids 1-79. The calpain cleaved form of ATG5 is missing amino acids 195-275.
About ATG5 and DyLight 350
ATG5 The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra