ATG5 / Alexa Fluor 350 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-53818AF350 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen ATG5
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 350
Target Species Bovine, Fish, Guinea Pig, Human, Mouse, Porcine, Primate, Rat, Xenopus, Zebrafish
Applications WB, FC, IHC, ICC/IF, IHC-P, Knockout Validated
Description This is selective for the full-length and calpain cleaved isoform proteins. The short isoform is missing amino acids 1-79. The calpain cleaved form of ATG5 is missing amino acids 195-275.
About ATG5 and Alexa Fluor 350
ATG5 The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra