ASC / DyLight 350 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-78978UV (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen ASC
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 350
Target Species Human, Mouse
Applications IHC, ICC/IF, IHC-P
Description Rabbit ASC/TMS1 antibody [DyLight 350] detects Human, Mouse
About ASC and DyLight 350
ASC This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra