ASC / Alexa Fluor 750 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-78977AF750 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen ASC
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 750
Target Species Human, Mouse, Rat
Applications WB, IHC, ICC/IF, IHC-P
Description Rabbit ASC/TMS1 antibody [Alexa Fluor 750] detects Human, Mouse, Rat
About ASC and Alexa Fluor 750
ASC This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
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Alexa Fluor 750 Excitation and Emission Spectra