Alkaline Phosphatase / PE-Cy5.5 / 8B6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-3638PECY55 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen Alkaline Phosphatase
Clone 8B6
Host Mouse
Isotype IgG2a κ
Conjugate PE-Cy5.5
Target Species Human, Mouse, Rat
Applications FC
Description Alkaline Phosphatase, Placental - both Regan and Nagao isoenzymes. No cross reactivity with other isoenzymes of Alkaline Phosphatase.
About Alkaline Phosphatase and PE-Cy5.5
Alkaline Phosphatase This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
PE-Cy5.5 PE-Cyanine®5.5 (PE-Cy5.5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5.5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5.5. PE-Cy5.5 has an excitation peak at 496 nm and an emission peak at 695 nm.
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PE-Cy5.5 Excitation and Emission Spectra