Vitamin D Receptor / Cy5.5 /
Vitamin D Receptor / Cy5.5 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-2987R-Cy5.5 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | Vitamin D Receptor | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy5.5 | |
| Target Species | Human, Mouse, Rat | |
| Applications |
About Vitamin D Receptor and Cy5.5
| Vitamin D Receptor | This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018] | |
|---|---|---|
| Cy5.5 | Cy5.5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 678 nm and an emission peak at 695 nm. Spectrally its similar to Alexa Fluor™ 680. |
Citations
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