CD49f / Alexa Fluor 647 / GoH3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-43400AF647 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen CD49f
Clone GoH3
Host Rat
Isotype IgG2a κ
Conjugate Alexa Fluor 647
Target Species Bovine, Human, Mouse
Applications FC, IHC-Fr, IHC
About CD49f and Alexa Fluor 647
CD49f The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 647 Excitation and Emission Spectra