Skp2 / Alexa Fluor 594 /
Skp2 / Alexa Fluor 594 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-1096R-A594 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | Skp2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Alexa Fluor 594 | |
| Target Species | Human, Mouse, Rat | |
| Applications | IHC-P | |
| Description | SKP2 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated |
About Skp2 and Alexa Fluor 594
| Skp2 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011] | |
|---|---|---|
| Alexa Fluor 594 | Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive. |
Citations
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