CD162 / Alexa Fluor 594 /
CD162 / Alexa Fluor 594 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-10253R-A594 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | CD162 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Alexa Fluor 594 | |
| Target Species | Mouse, Rat | |
| Applications | IHC-P | |
| Description | PSGL-1/CD162 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated |
About CD162 and Alexa Fluor 594
| CD162 | This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011] | |
|---|---|---|
| Alexa Fluor 594 | Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive. |
Citations
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