P-Cadherin / Alexa Fluor 750 /
P-Cadherin / Alexa Fluor 750 /
Product Details
Supplier | Bioss | |
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Catalog #: | bs-1159R-A750 (View supplier product page) | |
Size | 100 μl | |
Price | $468.00 | |
Antigen | P-Cadherin | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Alexa Fluor 750 | |
Target Species | Human, Mouse, Rat | |
Applications | IHC-P | |
Description | P-cadherin Polyclonal Antibody, ALEXA FLUOR 750 Conjugated |
About P-Cadherin and Alexa Fluor 750
P-Cadherin | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015] | |
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Alexa Fluor 750 | Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications. |