LC3 / Alexa Fluor 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-78964AF488 (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen LC3
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Bovine, Human, Mouse, Porcine, Primate, Rat
Applications WB, ICC/IF, IHC-P, IHC
Description This LC3I antibody specifically detects the cytosolic form of LC3 before it gets converted into LC3II during autophagy.
About LC3 and Alexa Fluor 488
LC3 MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra