Myelin Protein Zero / Cy5.5 /
Myelin Protein Zero / Cy5.5 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-0337R-Cy5.5 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | Myelin Protein Zero | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy5.5 | |
| Target Species | Human, Mouse, Rat | |
| Applications | IHC-P | |
| Description | Myelin Protein Zero Polyclonal Antibody, Cy5.5 Conjugated |
About Myelin Protein Zero and Cy5.5
| Myelin Protein Zero | This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015] | |
|---|---|---|
| Cy5.5 | Cy5.5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 678 nm and an emission peak at 695 nm. Spectrally its similar to Alexa Fluor™ 680. |
Citations
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