MS4A2 / Alexa Fluor 555 /
MS4A2 / Alexa Fluor 555 /
Product Details
Supplier | Bioss | |
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Catalog #: | bs-4870R-A555 (View supplier product page) | |
Size | 100 μl | |
Price | $468.00 | |
Antigen | MS4A2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Alexa Fluor 555 | |
Target Species | Mouse, Rat | |
Applications | IHC-P | |
Description | MS4A2 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated |
About MS4A2 and Alexa Fluor 555
MS4A2 | The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012] | |
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Alexa Fluor 555 | Alexa Fluor™ 555 (AF555, Alexa 555) has an excitation peak at 555 nm and an emission peak at 565 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 555 (ATT Bioquest) and iFluor® 560 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 555 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications. |