CD25 / Cy5.5 /
CD25 / Cy5.5 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-0577R-Cy5.5 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | CD25 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy5.5 | |
| Target Species | Human, Mouse, Rat | |
| Applications | IHC-P | |
| Description | IL2RA Polyclonal Antibody, Cy5.5 Conjugated |
About CD25 and Cy5.5
| CD25 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] | |
|---|---|---|
| Cy5.5 | Cy5.5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 678 nm and an emission peak at 695 nm. Spectrally its similar to Alexa Fluor™ 680. |
Citations
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