GAD65 / Alexa Fluor 647 /
GAD65 / Alexa Fluor 647 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-0400R-A647 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | GAD65 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Alexa Fluor 647 | |
| Target Species | Human, Mouse, Rat | |
| Applications |
About GAD65 and Alexa Fluor 647
| GAD65 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] | |
|---|---|---|
| Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Citations
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