FGF-R2 / Alexa Fluor 680 /
FGF-R2 / Alexa Fluor 680 /
Product Details
Supplier | Bioss | |
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Catalog #: | bs-0675R-A680 (View supplier product page) | |
Size | 100 μl | |
Price | $468.00 | |
Antigen | FGF-R2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Alexa Fluor 680 | |
Target Species | Human, Mouse, Rat | |
Applications | FC | |
Description | FGFR2 Polyclonal Antibody, ALEXA FLUOR 680 Conjugated |
About FGF-R2 and Alexa Fluor 680
FGF-R2 | The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009] | |
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Alexa Fluor 680 | Alexa Fluor™ 680 (AF680, Alexa 680) has an excitation peak at 679 nm and an emission peak at 702 nm, and is spectrally similar to Cy®5.5 (GE Healthcare), IR680® (Licor), iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 680 is commonly used for flow cytometry, fluorescence microscopy and super-resolution microscopy. |