Estrogen Receptor alpha / Cy5 /
Estrogen Receptor alpha / Cy5 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-0122R-Cy5 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | Estrogen Receptor alpha | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy5 | |
| Target Species | Human, Mouse, Rat | |
| Applications | FC | |
| Description | Estrogen Receptor alpha Antibody, Cy5 Conjugated |
About Estrogen Receptor alpha and Cy5
| Estrogen Receptor alpha | This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020] | |
|---|---|---|
| Cy5 | Cy5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 649 nm and an emission peak at 667 nm. Spectrally its similar to Alexa Fluor™ 647. |
Citations
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