RANTES / Cy5 /
RANTES / Cy5 /
Product Details
| Supplier | Bioss | |
|---|---|---|
| Catalog #: | bs-1324R-Cy5 (View supplier product page) | |
| Size | 100 μl | |
| Price | $468.00 | |
| Antigen | RANTES | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy5 | |
| Target Species | Bovine, Human, Mouse | |
| Applications | IHC-P | |
| Description | CCL5/RANTES Polyclonal Antibody, Cy5 Conjugated |
About RANTES and Cy5
| RANTES | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] | |
|---|---|---|
| Cy5 | Cy5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 649 nm and an emission peak at 667 nm. Spectrally its similar to Alexa Fluor™ 647. |
Citations
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