NOD2 / Alexa Fluor 647 /
NOD2 / Alexa Fluor 647 /
Product Details
Supplier | Bioss | |
---|---|---|
Catalog #: | bs-7084R-A647 (View supplier product page) | |
Size | 100 μl | |
Price | $468.00 | |
Antigen | NOD2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Alexa Fluor 647 | |
Target Species | Human, Mouse, Rat | |
Applications | IHC-P | |
Description | CARD15 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated |
About NOD2 and Alexa Fluor 647
NOD2 | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014] | |
---|---|---|
Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |