Dnmt1 / DyLight 350 / 60B1220.1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-56519UV (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen Dnmt1
Clone 60B1220.1
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 350
Target Species Bovine, Human, Mouse, Porcine, Rat, Sheep
Applications WB, IHC-P, FC, ICC/IF, IHC-Fr, IHC, KD
Description Mouse DNMT1 antibody reacts with Human, Mouse, Rat, Porcine, Bovine, Sheep [DyLight 350]
About Dnmt1 and DyLight 350
Dnmt1 This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra