NOD2 / Alexa Fluor 488 / 2D9

Citations: (1)
Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-524AF488 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen NOD2
Clone 2D9
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Human, Mouse
Applications WB, FC, ICC/IF, IHC-P, IHC, ICFC
Description Mouse NOD2 antibody reacts with Human, Mouse [Alexa Fluor 488]
About NOD2 and Alexa Fluor 488
NOD2 This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Citations
PMID 28241127
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Alexa Fluor 488 Excitation and Emission Spectra