B1 Bradykinin Receptor / Alexa Fluor 647 /
B1 Bradykinin Receptor / Alexa Fluor 647 /
Product Details
Supplier | Bioss | |
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Catalog #: | bs-8675R-A647 (View supplier product page) | |
Size | 100 μl | |
Price | $468.00 | |
Antigen | B1 Bradykinin Receptor | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Alexa Fluor 647 | |
Target Species | Human, Mouse, Rat | |
Applications |
About B1 Bradykinin Receptor and Alexa Fluor 647
B1 Bradykinin Receptor | Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq, Aug 2020] | |
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Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |