Supervillin / APC /
Supervillin / APC /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C740793-200 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | Supervillin | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | WB | |
| Description | SVIL / Supervillin Antibody (aa1617-1788, APC) |
About Supervillin and APC
| Supervillin | This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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