PGC / APC /
PGC / APC /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C738368-1 (View supplier product page) | |
| Size | 1 ml | |
| Price | ||
| Antigen | PGC | |
| Clone | ||
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | WB | |
| Description | PGC / Pepsin C Antibody (aa61-388, APC) |
About PGC and APC
| PGC | This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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