CIDEA / APC-Cy7 /
CIDEA / APC-Cy7 /
Product Details
Supplier | LifeSpan | |
---|---|---|
Catalog #: | LS-C737386-100 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | CIDEA | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC-Cy7 | |
Target Species | Human | |
Applications | WB | |
Description | CIDEA / CIDE-A Antibody (aa1-219, APC, Cy7) |
About CIDEA and APC-Cy7
CIDEA | This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010] | |
---|---|---|
APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |