Dnmt3b / APC-Cy7 /
Dnmt3b / APC-Cy7 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C737102-200 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | Dnmt3b | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | APC-Cy7 | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | DNMT3B Antibody (aa581-859, APC, Cy7) |
About Dnmt3b and APC-Cy7
| Dnmt3b | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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