CYP1A2 / APC-Cy7 /
CYP1A2 / APC-Cy7 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C735368-200 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | CYP1A2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | APC-Cy7 | |
| Target Species | Human | |
| Applications | WB | |
| Description | CYP1A2 Antibody (aa2-231, APC, Cy7) |
About CYP1A2 and APC-Cy7
| CYP1A2 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
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