GRPR / APC-Cy7 /
GRPR / APC-Cy7 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C734598-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | GRPR | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | APC-Cy7 | |
| Target Species | Human | |
| Applications | WB | |
| Description | GRPR Antibody (aa1-114, APC, Cy7) |
About GRPR and APC-Cy7
| GRPR | Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
| Additional Sources |
|
|---|
