CD305 / APC-Cy7 /
CD305 / APC-Cy7 /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C731873-100 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | CD305 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC-Cy7 | |
Target Species | Human | |
Applications | WB | |
Description | LAIR1 / CD305 Antibody (aa40-208, APC, Cy7) |
About CD305 and APC-Cy7
CD305 | The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] | |
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APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |