CD263 / APC-Cy7 /
CD263 / APC-Cy7 /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C729745-100 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | CD263 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC-Cy7 | |
Target Species | Human | |
Applications | WB | |
Description | TRAIL-R3 / DCR1 Antibody (aa32-244, APC, Cy7) |
About CD263 and APC-Cy7
CD263 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] | |
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APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |