RANTES / APC-Cy7 /
RANTES / APC-Cy7 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C729639-200 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | RANTES | |
| Clone | ||
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | APC-Cy7 | |
| Target Species | Canine | |
| Applications | WB | |
| Description | CCL5 / RANTES Antibody (aa24-91, APC, Cy7) |
About RANTES and APC-Cy7
| RANTES | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] | |
|---|---|---|
| APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
Citations
| Additional Sources |
|
|---|
