CD178 / APC-Cy7 /
CD178 / APC-Cy7 /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C729175-100 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | CD178 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | APC-Cy7 | |
Target Species | Human | |
Applications | WB | |
Description | FASLG / Fas Ligand Antibody (aa103-281, APC, Cy7) |
About CD178 and APC-Cy7
CD178 | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] | |
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APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |