Perforin / DyLight 350 / CB5.4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-97512UV (View supplier product page)
Size 0.1 ml
Price $609.00
Antigen Perforin
Clone CB5.4
Host Rat
Isotype IgG2a
Conjugate DyLight 350
Target Species Mouse
Applications WB, IHC-Fr, IHC-P, ICC/IF, FC, IHC
Description Recognizes mouse perforin (region aa 402-534).
About Perforin and DyLight 350
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra