Filaggrin / PE /
Filaggrin / PE /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C728166-200 (View supplier product page) | |
Size | 200 μl | |
Price | ||
Antigen | Filaggrin | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | PE | |
Target Species | Human | |
Applications | WB | |
Description | FLG / Filaggrin Antibody (aa3905-4031, PE) |
About Filaggrin and PE
Filaggrin | The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |