GBA / PE /
GBA / PE /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C725654-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | GBA | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | PE | |
| Target Species | Rat | |
| Applications | WB | |
| Description | GBA / Glucosidase Beta Acid Antibody (aa248-508, PE) |
About GBA and PE
| GBA | This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
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