Caspase 4 / PE /
Caspase 4 / PE /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C724288-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | Caspase 4 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | PE | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | CASP4 / Caspase 4 Antibody (aa81-266, PE) |
About Caspase 4 and PE
| Caspase 4 | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
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