GAD1 / APC /
GAD1 / APC /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C718094-1 (View supplier product page) | |
| Size | 1 ml | |
| Price | ||
| Antigen | GAD1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | APC | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | GAD1 / GAD67 Antibody (aa1-97, APC) |
About GAD1 and APC
| GAD1 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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