KRT81 / HRP /
KRT81 / HRP /
Product Details
Supplier | LifeSpan | |
---|---|---|
Catalog #: | LS-C714746-200 (View supplier product page) | |
Size | 200 μl | |
Price | ||
Antigen | KRT81 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | HRP | |
Target Species | Human | |
Applications | WB | |
Description | KRT81 / Keratin 81 / KRTHB1 Antibody (aa142-257, HRP) |
About KRT81 and HRP
KRT81 | The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008] |
---|