ASC / DyLight 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-78977G (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen ASC
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Human, Mouse, Rat
Applications IHC-P, ICC/IF, WB, IHC
Description Rabbit ASC/TMS1 antibody [DyLight 488] detects Human, Mouse, Rat
About ASC and DyLight 488
ASC This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

DyLight 488 Excitation and Emission Spectra