LIF R alpha / HRP /
LIF R alpha / HRP /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C707679-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | LIF R alpha | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | HRP | |
| Target Species | Human | |
| Applications | WB | |
| Description | CD118 / LIF Receptor Alpha Antibody (aa45-184, HRP) |
About LIF R alpha and HRP
| LIF R alpha | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018] |
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Citations
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