IFNGR1 / DyLight 755 / BB1E-2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64793IR (View supplier product page)
Size 100 μl
Price $399.00
Antigen IFNGR1
Clone BB1E-2
Host Mouse
Isotype IgG2a
Conjugate DyLight 755
Target Species Bovine, Human
Applications WB, FC, ELISA, IHC-Fr, IHC
Description In Western Blotting only one protein band is stained corresponding to a MW of 43,000, which is equal to the MW for the glycosylated extracellular part of the human extra-cellular interferon-gamma receptor (fused to c-myc), and a MW of 27,000 corresponding to the non-glycosylated part (fused to c-myc). The antibody does not neutralise biological activity of interferon gamma.
About IFNGR1 and DyLight 755
IFNGR1 This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra